4 edition of hemopoietic colony stimulating factors found in the catalog.
|LC Classifications||QP92 .M483 1984|
|The Physical Object|
|Pagination||xv, 493 p. :|
|Number of Pages||493|
|LC Control Number||84008076|
Abstract: Hemopoietic colony stimulating factors (HCSFs) are naturally occurred substances that are released in response to infection or inflammation and regulate the proliferation and differentiation of hemopoietic progenitor cells. Some representative members of this peptide family induce atherogenesis through the mediation of monocyte. Abstract: Hemopoietic colony stimulating factors (HCSFs) are naturally occurred substances that are released in response to infection or inflammation and regulate the proliferation and differentiation of hemopoietic progenitor cells. Some representative members of this peptide family induce atherogenesis through the mediation of monocyte Cited by:
A novel function of granulocyte colony-stimulating factor in mobilization of human hematopoietic progenitor cells Article (PDF Available) in Immunology and Cell Biology 87(5) April Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate into a specific kind of blood cell (usually white blood cells.
Granulocyte colony-stimulating factors (G-CSF) and granulocyte-macrophage colony-stimulating factors (GM-CSF) are substances that bind to hemopoietic stem cells, activating them to proliferate and differentiate into granulocytes and macrophages—the specific cell type of interest. Colony-stimulating factors administered in an oral rinse have been evaluated for effect to prevent and manage. Production of hematopoietic colony-stimulating factors by human natural killer cells. M C Cuturi Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania Cited by:
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The colony-stimulating factors (CSFs) are the major regulators in hemopoietic colony stimulating factors book body of the production and activity of two types of white blood cells--granulocytes and macrophages.
CSFs are used by clinicians to treat patients with damaged immune systems, for example, as a result of by: Description. The colony-stimulating factors (CSFs) are the major regulators in the body of the production and activity of two types of white blood cells - granulocytes and macrophages.
This book provides a detailed account of the discovery of the CSFs, their structure, molecular biology and cellular receptors, 5/5(1). The colony-stimulating factors (CSFs) are the major regulators in the body of the production and activity of two types of white blood cells--granulocytes and macrophages.
CSFs are used by clinicians to treat patients with damaged immune systems, for example, as a result of chemotherapy. Additional Physical Format: Online version: Metcalf, Donald. Hemopoietic colony stimulating factors. Amsterdam ; New York: Elsevier, (OCoLC) Get this from a library.
The hemopoietic colony-stimulating factors: from biology to clinical applications. [Donald Metcalf; Nicos Nicola] -- This book provides a detailed and up-to-date account of the discovery of the CSFs, their structure, molecular biology, and cellular receptors, the biology of the CSFs in vivo and in vitro, and their.
Hemopoietic Colony Stimulating Factors. Abstract. The concept that the continuous formation of blood cells might be under the control of specific humoral regulatory factors received early support from the demonstration that a humoral factor, termed erythropoietin, was involved in the regulation of erythropoiesis (Carnot and Deflandre, ).Cited by: Granulocyte colony stimulating factor (G-CSF), or colony-stimulating factor 3, is a glycoprotein cytokine that stimulates formation of granulocyte colonies from the proliferation of a single hematopoietic stem cell.
G-CSFs can be used to treat or prevent File Size: KB. Two hematopoietic growth factors, granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF), regulate the production and deployment of neutrophils. Both CSFs stimulate cell division and accelerate marrow transit times.
Leukine (sargramostim) is a recombinant human granulocyte‐macrophage colony stimulating factor (rhu GM‐CSF) produced by recombinant DNA technology in a yeast (S. cerevisiae) expression system. GM‐CSF is a hematopoietic growth factor which stimulates proliferation and differentiation of hematopoietic progenitor cells.
Ozer H, Armitage JO, Bennett CL, et al: update of recommendations for the use of hematopoietic colony-stimulating factors: Evidence-based, clinical practice guidelines. American Society of Clinical Oncology Growth Factors Expert by: The hematopoietic colony-stimulating factors (CSFs) have been introduced into clinical practice as additional supportive measures that can reduce the likelihood of.
The complementary DNAs and genes encoding the four major human myeloid growth factors--granulocyte colony-stimulating factor, macrophage colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and interleukinhave all been molecularly cloned.
These DNA clones have proved valuable for studying the molecular biology of these important regulatory Cited by: Pain is one of the many debilitating side effects of cancer. Now, Rohini Kuner and her colleagues show that blocking hematopoietic colony-stimulating factor Cited by: Granulocyte-macrophage colony-stimulating factor and granulocyte CSF are given to stimulate white blood cell formation in cancer patients who are receiving chemotherapy, which tends to kill their red bone marrow cells as well as the cancer cells.
Thrombopoietin shows great promise for preventing platelet depletion during chemotherapy. CSFs and thrombopoietin also improve the outcome of patients who Angiopoietin: Agonists: Angiopoietin 1, Angiopoietin 4. Donald Metcalf is the author of The Hemopoietic Colony Stimulating Factors ( avg rating, 1 rating, 0 reviews, published ), Blood Lines ( avg /5(3).
Colony Stimulating Factors (CSF) are hematopoietic growth factors, which act on progenitor cells capable of forming either single differentiated (lineage-specific) cell types, such as the neutrophilic granulocyte, or forming several differentiated cell types (i.e., non-lineage-specific).
The complementary DNAs and genes encoding the four major human myeloid growth factors--granulocyte colony-stimulating factor, macrophage colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and interleukinhave all been molecularly cloned. These DNA clones have proved valuable for studying the molecular biology of these important regulatory.
Hematopoietic Growth Factors in Oncology reviews and integrates the major advances in our understanding of the underlying molecular biology and pharmacology of these agents along with the results of well designed and executed randomized controlled trials of the erythroid stimulating agents, the myeloid growth factors and the new thrombopoietic.
Macrophage Colony-Stimulating Factor Receptor. The known ligands of macrophage colony-stimulating factor 1 receptor (CSF-1R) are CSF-1 and interleukin (IL) 4 CSF-1 was the first hemopoietic growth factor to be isolated, and it can promote the growth of pure colonies of.
Hematopoietic colony stimulating factors (CSF) regulate the growth and development of phagocytic cell progenitors and also augment functional activation of phagocytes. Granulocyte-CSF (G-CSF) is. Hematopoietic colony-stimulating factors (CSFs) — also known as white blood cell growth factors — reduce the duration and severity of neutropenia, as .This review evaluated the efficacy of colony-stimulating factors (CSFs) in patients with cancer and in those undergoing stem-cell transplantation.
The authors concluded that CSFs have no significant effects on short-term all-cause mortality or infection-related mortality, but that CSF prophylaxis reduces the duration of febrile neutropenia, hospitalisation and documented infections.Ringden O, Hassan Z, Karlsson H, et al. Granulocyte colony-stimulating factor induced acute and chronic graft-versus-host disease.
Transplantation ; Soff GA, Miao Y, Bendheim G, et al. Romiplostim treatment of chemotherapy-induced thrombocytopenia. J .